To maximize ROI, buyers should leverage tiered pricing models; typically, increasing an order from 500 to 2,000 units can reduce the unit cost by 15-25%. Requesting FOB (Free On Board) pricing is generally more cost-effective for large volumes as it allows the buyer to control shipping contracts. For startups, look for suppliers on Made-in-China.com that offer flexible MOQs (Minimum Order Quantities) of 50-100 units for 'Ready to Ship' styles, which allows for market testing without heavy inventory risk. Always factor in the Total Cost of Ownership (TCO), including customs duties, which can vary significantly based on the HS Code (typically 6205 for men's shirts) and the country of origin's trade agreements.