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The most critical component is Lumbrokinase, a group of proteolytic enzymes. High-quality extracts are usually standardized by enzyme activity (IU/mg) rather than just weight. Other vital indicators include protein content (typically >50%), amino acid profile, and the extraction method used (e.g., freeze-drying/lyophilization to preserve bioactivity).
It is widely used in the pharmaceutical industry for cardiovascular health supplements due to its fibrinolytic activity. It also serves as a premium ingredient in cosmetics for skin regeneration and as a high-protein bio-activator in specialized animal feed or organic fertilizers.
For health supplements, ensure the supplier holds GMP (Good Manufacturing Practice) and ISO 22000 certifications. If the product is intended for the US market, FDA registration and GRAS (Generally Recognized as Safe) status are essential. For European markets, check for REACH compliance and Novel Food authorizations where applicable.
Earthworms can bioaccumulate toxins, so it is mandatory to request Third-Party Lab Reports (COA). These reports must confirm that Heavy Metals (Lead, Arsenic, Mercury) and Pesticide Residues are within international safety limits. Additionally, verify microbiological safety (absence of E. coli and Salmonella).
Earthworm extract is sensitive to heat and moisture. Buyers should insist on vacuum-sealed aluminum foil packaging and, for high-activity enzymes, specify cold-chain logistics (2-8°C). Ensure the supplier includes desiccants and uses UV-protected containers to prevent oxidation.
Focus negotiations on Activity Levels (IU) rather than just price per kilogram. A lower price often indicates lower enzyme potency. Request a pre-shipment sample from the actual production batch and use Made-in-China.com's secured payment services to hold funds until the third-party inspection confirms the sample matches the bulk order.
Biological products often require a Phytosanitary Certificate or an Import Permit depending on the destination country's agricultural laws. Always consult with a professional customs broker to confirm the correct HS Code (typically 2932 or 3507) to avoid misclassification fines and shipment seizures.
Utilize the Audit Reports available on Made-in-China.com to verify the supplier's factory existence and production capacity. Avoid direct wire transfers to private accounts; instead, use Trade Assurance or Letters of Credit (L/C) for large volumes to ensure the seller complies with all shipping and quality documentation before payment is released.