
Guaiazulene CAS 489-84-9 C15h18 1, 4-Dimethyl-7- (1-methylethyl) -Azulen

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Guaiazulene (CAS No. 489-84-9) is a dark blue crystalline hydrocarbon. For pharmaceutical and high-end cosmetic applications, you must ensure a purity level of ≥99%. Key technical indicators include a melting point of 31°C to 33°C and a heavy metal content of <10ppm. Always request a Certificate of Analysis (COA) and Gas Chromatography (GC) reports to verify the absence of residual solvents and impurities.
Depending on the target market, the supplier must provide MSDS (Material Safety Data Sheet) for safe handling. For the US market, ensure the ingredient is INCI registered and compliant with FDA regulations. For the EU, REACH registration is essential. If used in medical grade products, look for suppliers with GMP (Good Manufacturing Practice) certification to ensure batch-to-batch consistency and safety.
Guaiazulene is highly sensitive to light and heat, which can lead to degradation and discoloration. It must be stored in amber glass bottles or light-shielded aluminum containers. The storage temperature should be kept below 25°C (ideally 2-8°C for long-term storage). When sourcing, confirm that the supplier uses nitrogen-flushed packaging to prevent oxidation during transit.
Guaiazulene is primarily used for its anti-inflammatory and anti-allergic properties. Cosmetic Grade is used in skincare for soothing sensitive skin, while Pharmaceutical Grade is used in gastrointestinal medicines and dental care products. Ensure you specify the application to the supplier, as particle size and solubility requirements may vary between oil-based ointments and aqueous solutions.
Utilize third-party inspection services (such as SGS or Intertek) to conduct pre-shipment testing. For new suppliers on Made-in-China.com, start with a small sample order and perform independent lab testing. Ensure the contract specifies that the final payment is contingent upon the product meeting the COA specifications verified by your local lab.
Focus on volume-based pricing tiers; typically, purchasing in 25kg drums offers a 15-20% discount compared to 1kg units. Negotiate for long-term supply agreements to lock in prices, as the market price of Guaiazulene can fluctuate based on the availability of raw materials like guaiac wood oil. Request free samples (shipping paid by buyer) to establish a quality baseline.
Since Guaiazulene has a low melting point (31°C), it may liquefy during summer transit or in tropical climates. Request temperature-controlled shipping (Reefer containers) or insulated packaging for air freight. Ensure the shipping documents clearly label it as a non-hazardous chemical (unless concentrated/mixed otherwise) to avoid unnecessary customs delays, but always include the MSDS for customs clearance.
Always use Secure Payment services provided by Made-in-China.com to protect your funds until delivery is confirmed. Verify the supplier's Export License for chemical products and ensure the HS Code (typically 2902.90) is correctly declared to avoid tariff penalties or seizure by customs due to misclassification.