To optimize costs, analyze the Total Cost of Ownership (TCO) beyond the unit price. For manual brushes, unit prices often drop by 20-40% when ordering in quantities exceeding 50,000 units. For electric toothbrushes, focus on the battery life (lithium-ion vs. NiMH) and the cost of replacement heads, as these drive long-term consumer value. Sourcing from integrated manufacturers on Made-in-China.com can reduce costs by eliminating middleman markups and allowing for OEM/ODM customization at lower thresholds.